Hepatic stellate cell proliferation: A potential role of protein kinase R
نویسندگان
چکیده
منابع مشابه
Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential.
UNLABELLED Cathepsins have been best characterized in tumorigenesis and cell death and implicated in liver fibrosis; however, whether cathepsins directly regulate hepatic stellate cell (HSC) activation and proliferation, hence modulating their fibrogenic potential, is largely unknown. Here, we show that expression of cathepsin B (CtsB) and cathepsin D (CtsD) is negligible in quiescent HSCs but ...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2011
ISSN: 0270-9139
DOI: 10.1002/hep.24579